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OUR SCIENCE

Genomics

Genomics

What is the Human Genome, and how does this affect me?

Genes are made up of DNA (Deoxyribonucleic acid) and are the template to make proteins. We have two copies of each gene, one inherited from each parent.

Human DNA consists of over 3 billion nucleotide base pairs, more than 99% of which are identical in each us. The remainder contains small variations known as SNPs (Single Nucleotide Polymorphisms).

DNA

Discover How Your DNA Personalizes Your Healthcare. Explore Your Past and Shape Your Future. “Genomic medicine is an emerging medical discipline that involves using genomic information about an individual as part of their clinical care (e.g. for diagnostic or therapeutic decision-making) and the health outcomes and policy implications of that clinical use.”  -National Institute of Health

SNP

A SNP is a variation in a single nucleotide that occurs at specific position in the genome.

Usually, SNPs alone will not cause disease; rather they convey a susceptibility to disease and change the responsiveness to environmental exposures.

TRIUMPH

Replace trial and error with triumph. Genomics provide the blue print for your body’s molecular framework and how your body responds to the world around you. Because you are unique, the traditional “one-size-fits-all” approach simply doesn’t work. Genomic information can be used as part of clinical care (e.g. for diagnostic or therapeutic decision-making) and provide clues for what actions will work best for you.

“Genomic medicine is an emerging medical discipline that involves using genomic information about an individual as part of their clinical care (e.g. for diagnostic or therapeutic decision-making) and the health outcomes and policy implications of that clinical use.” -National Institute of Health

THE VALUE OF GENOMIC TESTING IN PRECISION MEDICINE

Genomic testing assesses the presence of the unique genetic variations each individual possesses.

SNPs can have a profound effect on the functioning of the genes in which they are found. This in turns effects the biological pathway in which the gene is active, affecting metabolic functions that are important for maintaining a state of health.

Translating this information offers a powerful a health advantage, enabling the Institute for Human Optimization to prescribe precises lifestyle  and nutritional recommendations aimed at compensating for the genetic variations.

Clinical Value

Genetic factors can account for up to 95% of drug-response variability and susceptibility 1. In other words, how a drug will—or won’t—work for a particular individual. The Institute for Human Optimization testing brings Genomic Medicine to everyone, identifying how a patient’s DNA and current medications may affect their response to drugs and clinical nutrition.

  1. Kalow W, et al. Pharmacogenetics 1998;8:283-289
  • Highlights specific metabolic pathways that require additional support
  • Provides recommendations that involve optimization of vitamins and minerals
  • Suggests whether an individual is better able to reduce their cholesterol levels through diet, as opposed to medication
  • Provides an indication of the degree of susceptibility to the harmful effects of carcinogens ingested in the diet
  • Provides  strategies for weight management based on genetic make-up
  • Provides an understanding of why previous weight management programs may have been unsuccessful
  • Provides insight to which diet type (e.g. Mediterranean style, carbohydrate, low fat diet) may be most suited to an individual to manage weight based on genotype.

Precision Medicine. Informed Care.

PHARMACOGENOMICS

Your DNA determines which drugs you will clinically respond to.  It also provides information to determine the right drug, for the right patient at the right dose. Stop wondering which medication is right for you and the one size-fits-all approach to pharmacological intervention

MICROBIAL GENOMICS

By taking care of your 40 trillion microbial friends, you can maximize your wellness and potentially prevent disease. These microorganisms – which make up your gut microbiome – have been implicated in maintaining optimal health, as well as many chronic conditions, including diabetes, obesity, Alzheimer’s, Parkinson’s, coronary artery disease, psoriasis, lupus, and autism.

NUTRIGENOMICS

Your DNA affects the way your body interacts with the foods and nutritional supplements. By analyzing your DNA, we are able to gain valuable insight into what foods are most beneficial to your health and determine which supplements are right for you.

WELLNESS GENOMICS

Obesity, Injury Risk, Inflammation, Vitamin Absorption, Detoxification, Diabetes Risk, Cholesterol, Food Response, Weight loss and Gum Health.

Navigating the landscape of individualized health begins with engagement. Understanding the value proposition of investment into self-well-being is consequential. With the Institute for Human Optimization, every client engagement starts with the development of an Individualized Wellness Map.

Through this consultative process we define a vision, employ strategic objectives, execute skillful tactics, and establish success metrics to facilitate your specific goals customized to your definition of success.

We offer on-site trainings, digital continuity platforms, live support for your organization.