EBOO / EBO2 (Extracorporeal Blood Oxygenation and Ozonation) is an advanced regenerative therapy in which blood is filtered, oxygenated, ozonated, and optionally treated with photobiomodulation outside the body before being safely reinfused. It is used to support detoxification, mitochondrial function, immune regulation, and systemic resilience.

How long does an EBOO session take?

Most EBOO treatments take between 60 and 90 minutes, depending on your individualized protocol and whether photobiomodulation is included.

At the Institute for Human Optimization, EBOO is performed under direct physician oversight using sterile, single-use tubing circuits and medical screening to ensure appropriate candidacy. Your provider monitors your comfort, vitals, and flow parameters throughout the session.

Who is a good candidate for EBOO?

EBOO may be considered for individuals experiencing systemic inflammation, immune dysregulation, toxin burden, mitochondrial dysfunction, long-haul symptoms, oxidative stress, recovery challenges, or those pursuing longevity and cellular optimization under physician guidance.

How many EBOO sessions do I need?

Many patients start with a series of EBOO sessions for cumulative benefits. Your physician will recommend a frequency based on your goals, lab data, and clinical response.

How much does EBOO cost?

At the Institute for Human Optimization, an EBOO consult is $300, a single session is $1800, and a three-session package is $4500. Pricing reflects physician oversight, sterile single-use circuits, and individualized protocols.

Do I need a consultation before my first EBOO session?

Yes. A medical consultation is required to assess candidacy, review labs and medications, and design your personalized EBOO protocol. Existing patients may not require an additional consult.

Can EBOO help with long-haul or post-infectious symptoms?

Many long-haul or post-infectious patients seek EBOO due to its effects on inflammatory burden, oxidative stress, and mitochondrial function. Your provider will determine whether EBOO is appropriate during your consultation.

No. Most patients find EBOO to be comfortable. It is performed through a single IV line, and flow rates are adjusted for comfort and safety.

Regenerative Medicine • Extracorporeal Therapy

EBOO / EBO₂ Therapy for Advanced Detoxification & Cellular Optimization

A next-generation extracorporeal therapy that filters, oxygenates, ozonates, and illuminates your blood outside the body — supporting detoxification, reducing inflammation, and optimizing cellular function from the inside out.

Blood Filtration & Purification Controlled Oxygenation External Ozonation Multi-Wavelength Light Therapy Reduced Inflammation Enhanced Cellular Energy

Schedule an Consultation How EBOO / EBO₂ Works

Regenerative Medicine • EBOO / EBO₂

What Is EBOO / EBO₂?

EBOO, or Extracorporeal Blood Oxygenation and Ozonation, is an advanced regenerative therapy that works through a closed extracorporeal circuit. Your blood is gently removed, purified, oxygenated, exposed to medical grade ozone outside the body, and then returned in a revitalized state. This process supports deeper detoxification, improved cellular energy, immune regulation, and enhanced systemic resilience.

Filtration

EBOO uses a medical grade filter to remove inflammatory proteins, toxins, microclots, and circulating waste that place stress on the immune system. This supports a lower inflammatory burden and a cleaner internal environment.

Oxygenation and Ozonation

As blood circulates through the extracorporeal loop, it is enriched with concentrated oxygen and exposed to carefully controlled medical grade ozone outside the body. This supports mitochondrial function, cellular signaling, and purification without ozone entering the circulation directly.

Photobiomodulation

With the Hemealumen chamber, EBOO can include multi wavelength light to support cellular pathways. Red, blue, green, amber, UVA, and UVC light can be layered to enhance detoxification, immune balance, and recovery in a highly targeted way.

EBOO is not simply ozone therapy. It is a multi stage regenerative system designed to support cellular optimization and reduce inflammatory burden.

How EBOO / EBO₂ Works

A Step by Step Regenerative Circuit

EBOO uses a closed extracorporeal circuit to gently remove blood, guide it through filtration, oxygenation, ozonation, and optional light activation, then return it in a revitalized state. Each stage is designed to support detoxification, cellular energy, and immune balance in a controlled and precise way.

Step 1 — Gentle Blood Collection

Blood is drawn through a small intravenous line and guided into a sterile extracorporeal circuit. Flow is carefully regulated for comfort and safety.

Step 2 — Filtration

The blood passes through a specialized filter that removes inflammatory proteins, microclots, and circulating waste that place stress on the immune and vascular systems.

Step 3 — Oxygenation

The circuit enriches the blood with concentrated oxygen to support mitochondrial function and energy production at the cellular level.

Step 4 — Controlled Ozonation

Medical grade ozone interacts with the blood outside the body. This allows for therapeutic signaling and purification while keeping ozone out of direct circulation.

Step 5 — Photobiomodulation (Optional)

In protocols that include the Hemealumen device, multi wavelength light such as red, blue, green, amber, UVA, and UVC can be applied to support cellular signaling, detoxification pathways, and immune balance.

Step 6 — Reinfusion and Integration

The filtered, oxygenated, and conditioned blood is returned to the body through the IV line. Over time, this may support lower inflammatory load, improved energy, and a greater sense of systemic resilience.

Explore Each Stage of the EBOO Circuit

Step 1 — Gentle Blood Collection

A small intravenous line guides blood into the extracorporeal circuit in a controlled, comfortable way.

Step 2 — Filtration

Specialized filtration helps reduce inflammatory proteins and microclots that can interfere with circulation and recovery.

Step 3 — Oxygenation

Oxygen enrichment supports mitochondrial function and sustained cellular energy production.

Step 4 — Controlled Ozonation

Ozone engages with the blood outside the body, supporting signaling and purification while maintaining a high safety profile.

Step 5 — Photobiomodulation

Multi wavelength light can be layered to support immune balance, detoxification, and recovery based on individual needs.

Step 6 — Reinfusion

The revitalized blood is returned to the body where changes in inflammation, energy, and resilience unfold over time.

Patient Experience

What to Expect During EBOO / EBO₂

EBOO is a physician directed procedure performed in a calm, monitored setting. Your protocol is individualized, but most visits follow a similar flow. The cards below outline the key details so you know what to expect before your first session.

Treatment duration

Most EBOO sessions last between 60 and 90 minutes, depending on your protocol and whether photobiomodulation is included.

Treatment frequency

Frequency is individualized. Many patients begin with a series of EBOO sessions and then space treatments based on response, lab data, and long term goals.

Before your visit

Plan to arrive well hydrated, eat a light meal one to two hours before, and continue prescribed medications unless your provider gives different instructions.

After your session

Most patients return to normal activities the same day. Hydration, rest, and gentle movement can support detoxification. Your care team will review next steps before you leave.

Regenerative Medicine Insight

The role of EBOO in cellular optimization

EBOO supports systemic detoxification, improved mitochondrial function, and a lower inflammatory load. Together, these changes create conditions for better cellular signaling, resilience, and long term healthspan.

Pricing

EBOO / EBO₂ is a physician-directed regenerative therapy. Pricing reflects medical oversight, advanced equipment, and individualized protocols.

Regenerative Medicine Consultation

$300

A 30-minute medical evaluation to determine suitability for EBOO / EBO₂ and other regenerative therapies.

Existing patients may not require a consult. Please message us via the Patient Portal.

Single EBOO / EBO₂ Session

$1800

Full extracorporeal blood filtration, oxygenation, ozonation, and optional photobiomodulation depending on your protocol.

Save $900

3-Session EBOO / EBO₂ Package

$4500

Ideal for deeper detoxification, immune regulation, and cumulative therapeutic benefits over time.

Safety and Clinical Oversight

How we approach EBOO / EBO₂ safely

EBOO / EBO₂ at the Institute for Human Optimization is delivered in a medically supervised setting with individualized protocols. Every treatment is guided by your health history, labs, medications, and real time physiologic response.

Physician-directed protocols
Your EBOO plan is designed and overseen by a physician trained in regenerative and longevity medicine, with a focus on safety and appropriate patient selection.
Personalized screening
We review your cardiovascular status, medications, and key lab markers to determine candidacy and tailor the circuit settings, session frequency, and add-on therapies.
In-session monitoring
During your session, your comfort, vital signs, and overall tolerance guide how we adjust flow rates and parameters.
Sterile, single-use circuit
Each treatment uses a new, sterile extracorporeal tubing set and filter. Components are single use and not shared between patients.
Contraindication review
Conditions such as uncontrolled cardiovascular disease, active bleeding disorders, or significant anemia may require delaying or modifying treatment. Your provider will review this with you in detail before proceeding.

Candidacy

Who EBOO / EBO₂ May Help

EBOO / EBO₂ is considered for individuals navigating systemic inflammation, toxin burden, or chronic physiologic stress. It may also support those pursuing proactive healthspan and performance optimization.