Foundational layer
Genomics
Your inherited blueprint — SNP and polygenic risk patterns, pharmacogenomic signatures, detox and inflammatory genes.
The Biological Audit® · Foundational Diagnostic Program
A Head-to-Toe Multi-Omic Evaluation of Your Biology
A physician-led, systems-biology evaluation developed by Anil Bajnath, MD. It maps your current state of health, your aging trajectory, and the biological risk that routine bloodwork leaves invisible.
- More than 250 precision biomarkers across organ systems and molecular pathways
- Head-to-toe risk stratification for metabolic, cardiovascular, immune, and neurologic health
- An integrated report with a clear plan for correction, protection, and long-term optimization
Multi-omic analysis
Hallmarks of aging framework
Biological threat identification
Optional CancerCheck screening
Optional advanced imaging
CancerCheck screening and advanced imaging are optional additions, billed separately through the lab or partner facility. They complement, and do not replace, guideline-recommended cancer screening such as mammography and colonoscopy.
What Happens
From First Conversation to Your Plan
Four steps, roughly two months end to end. Most of that is laboratory time — whole genome sequencing and multi-omic analysis cannot be rushed without compromising what they tell us.
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01
Consultation
You meet with Anil Bajnath, MD to review your history, your goals, and what you want the data to answer. Together you determine which program fits.
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02
Specimen Collection
Collection is matched to your panel. Some programs need a single blood draw; others require several visits or additional sample types such as saliva. Elite and Concierge members can have collection arranged at their home, their place of work, or another convenient location within thirty miles of our office.
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03
Analysis and Interpretation
The laboratory processes your specimen while Dr. Bajnath builds your threat map and hallmarks profile, reading every result against your history rather than a population reference range.
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04
Results Review
You sit down with Dr. Bajnath and walk through the findings in full — what is stable, what is compensating, what needs attention now — and leave with your detailed report, your precision plan, and your digital twin.
Elite and Concierge continue from here with ongoing testing, monitoring, and recalibration. The Biological Audit® on its own concludes with your report and plan.
From Insight to Intervention
From Biological Audit to Precision Action Plan
The Biological Audit® is not a report. It is a roadmap. Once we have mapped your biomarkers, multi-omic signatures, and hallmarks of aging, we translate those findings into a precise, individualized strategy designed to improve your trajectory of health.
This is where data becomes medicine.
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01
Define Your Biological Priorities We organize your data into clear priorities: which molecular processes, organ systems, and aging mechanisms require immediate focus, and which are currently stable or outperforming your chronological age.
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02
Design Your Precision Intervention Strategy We architect a personalized plan across lifestyle, pharmacology, peptides, regenerative biologics, supplements, and environmental shifts — ranked by clinical impact and feasibility.
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03
Target the Drivers of Your Aging Pattern Every recommendation is mapped back to the hallmarks and mechanisms most active in your data — mitochondrial efficiency, senescence, inflammation, nutrient sensing, genomic stability, and more.
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Steps 1 through 3 complete the Biological Audit®. Steps 4 and 5 continue with Elite or Concierge.
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04
Implement With Physician-Led Guardrails You receive structured protocols, dosing guidance, and sequencing with physician oversight, so each intervention is implemented safely and in alignment with your biomarkers.
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05
Track, Reassess, and Recalibrate Your biology is dynamic. We repeat selected testing, monitor key biomarkers, and refine your plan as systems adapt — keeping your trajectory moving toward greater resilience and improved healthspan.
What It Is
Your Body, Read as One System
Most evaluations look at the body one symptom or one lab panel at a time. The Biological Audit® looks at how your systems behave together — how metabolism informs hormones, how immune activity shapes your aging trajectory, how gut and mitochondria influence cognition, how genes and environment interact over years.
Anil Bajnath, MD built it across a decade of treating complex metabolic, inflammatory, and age-related conditions, drawing on the systems-biology frameworks he teaches at George Washington University. He personally oversees every audit, so each data point is read against your physiology, your history, and your goals.
Founder
American Board of Precision Medicine
10+ years
Clinical practice in complex chronic disease
250+
Precision biomarkers per audit
What We Measure
From Molecules to Organs
Two views of the same biology. First how your organ systems are performing, then the molecular layers underneath that explain why.
Organ systems
- Brain and cognition Focus, memory, mood, neuroinflammatory signals.
- Cardiometabolic health Blood vessels, lipids, glucose control, inflammation.
- Immune and inflammatory balance Cytokines, chronic activation, immune resilience.
- Hormonal signaling Thyroid, adrenal, and sex hormones affecting energy, mood, and composition.
- Gut and microbiome Digestion, barrier integrity, nutrient absorption, microbial ecology.
Molecular data layers
Biological aging
Epigenomics
DNA methylation patterns and biological age estimates showing how lifestyle and exposure have shaped gene expression.
Real-time activity
Transcriptomics
mRNA expression trends, cellular stress responses, and immune activation patterns reflecting how your cells are responding now.
Signaling layer
Proteomics
Cytokines, growth and repair factors, and vascular proteins that reveal inflammation and nutrient-sensing activity.
Metabolic function
Metabolomics
Organic acid profiling, mitochondrial efficiency markers, and fatty acid balance — a biochemical fingerprint of your metabolism.
Gut ecosystem
Microbiomics
Microbial diversity, dysbiosis and barrier integrity, and the metabolites your gut ecosystem produces.
Life exposures
Exposomics
Environmental and toxin burden, stress and sleep impact, and circadian influences accumulated over time.
Clinical expression
Phenotypomics
Body composition, performance metrics, organ function, and hormone metabolite data — how the layers above show up in you.
Not a complete list. Your history, goals, and risks determine which systems and layers we emphasize within your Biological Audit®.
“When we understand your biology at the molecular, cellular, and systems level, we can intervene early, precisely, and meaningfully. That is the future of medicine and the purpose of the Biological Audit.”
Biological Age
Twelve Hallmarks, Measured Individually
Rather than reducing you to a single biological age number, we evaluate each of the twelve recognized hallmarks of aging against your multi-omic and clinical data — identifying which processes are stable, which are compensating, and which have begun to accelerate.
- Primary — the damage itself
- Genomic instability · Telomere attrition · Epigenetic alterations · Loss of proteostasis · Disabled macroautophagy
- Antagonistic — the body's response
- Deregulated nutrient sensing · Mitochondrial dysfunction · Cellular senescence
- Integrative — what you feel
- Stem cell exhaustion · Altered intercellular communication · Chronic inflammation · Microbiome disturbance
What We Find
Your Findings, Ranked by What Matters
The outcome is not more data. It is a map of the biological threats that matter most to your health, performance, and aging — six domains, each reported on the same three-point scale.
Stable
Compensating
Requires intervention
- Metabolic and cardiometabolic Early changes in glucose control, insulin dynamics, lipids, visceral fat, and vascular inflammation that raise risk for diabetes, cardiovascular disease, and metabolic syndrome.
- Inflammatory and immune Patterns of chronic low-grade inflammation, immune over-activation, or immune exhaustion that influence autoimmunity, infection risk, and the pace of aging.
- Cardiovascular and vascular Signals related to endothelial health, plaque formation, blood pressure patterns, and microvascular function that shape long-term heart and brain health.
- Neurologic and cognitive Markers connected to brain energy, neuroinflammation, sleep quality, mood, and cognitive performance that can signal decline long before symptoms appear.
- Hormonal and stress system Thyroid, adrenal, and sex hormone patterns, along with stress system load, that affect energy, weight, recovery, mood, and long-term resilience.
- Aging trajectory and resilience Biomarkers of aging, recovery capacity, and system flexibility that reveal whether you are aging faster, slower, or in line with your chronological age.
This map becomes the foundation for your strategy — what to address first, what to protect, and how to move from compensation to optimization.
Investment
Programs & Investment
The Biological Audit® is the diagnostic physical exam of the future. Where the annual checkup looks at a handful of surface markers, the Audit reads your biology across multiple omic layers — genomic, epigenetic, proteomic, metabolomic, and microbial — interpreted together by a physician and translated into a precision plan. Every program begins with a consultation, and capacity is deliberately limited.
Beyond the annual physical
A standard exam measures roughly a dozen values. The Audit evaluates thousands of data points across systems that interact.
Multiomic by design
Genome, epigenome, proteome, metabolome, and microbiome are read as one integrated picture rather than isolated reports.
Measured, not inferred
Every recommendation traces back to a measured value, and every value is re-measurable so change can be tracked over time.
Limited availability
Biological Audit
Foundational precision assessment with Dr. Anil Bajnath.
Program Investment
$2,500
One-time audit fee
- Comprehensive biological assessment
- Whole genome sequencing with clinical interpretation
- Core metabolic, cardiovascular, and inflammatory panels
- Physician-led results review and interpretation
- Personalized precision plan
Best for
Individuals who want a comprehensive understanding of how their body is functioning before making health decisions.
Request a consultationLimited availability
Biological Audit Elite
The full multiomic evaluation. The physical exam, reengineered.
Program Investment
$5,000
One-time audit fee
Everything in the Biological Audit, expanded
- Epigenetic profiling and biological age assessment
- Proteomic and metabolomic profiling
- Advanced cardiometabolic and lipoprotein particle analysis
- Inflammatory, immune, and oxidative stress markers
- Comprehensive endocrine and hormone evaluation
- Gut microbiome and micronutrient status analysis
- Environmental exposure and toxin burden screening
- VO₂ max and cardiopulmonary performance assessment
- Body composition and metabolic rate analysis
- Extended physician consultation and integrated precision plan
Optional
Ongoing Optimization Membership
Available after your audit. Continues the measurement cycle so your plan adjusts as your biology changes.
Membership Investment
Contact us
- Quarterly specialty lab testing
- Twice-yearly VO₂ max and performance medicine assessment
- Advanced functional and longevity diagnostics
- Quarterly optimization guided by your physician
- Personalized supplement and lifestyle protocols
- Ongoing progress monitoring
- Member pricing on all programs and regenerative medicine therapies
- Enhanced Longevity Gyms membership benefits
Best for
Individuals who want the deepest possible baseline of their biology, with the option to continue measuring and adjusting over time.
Request a consultationFifty patients per year
Concierge
A physician directing every decision.
Everything in Biological Audit Elite and the ongoing membership, plus
- Unlimited physician access
- Priority access and scheduling
- Continuous monitoring and strategy adjustments
- Specialist and care team coordination
- Expanded Longevity Gyms benefits
- White-glove concierge coordination
Best for
Executives, entrepreneurs, and individuals who want a physician directing every aspect of their health strategy.
Request a consultationWhat does multiomic actually mean?
An "ome" is a complete set of one type of biological molecule. Multiomics is the integrated analysis of several of those layers at once — the genome (your DNA sequence), the epigenome (chemical marks that regulate which genes are switched on), the proteome (the proteins your cells are actually producing), the metabolome (the small molecules produced by metabolism), and the microbiome (the bacterial populations in your gut). Each layer answers a different question: your genome describes predisposition, while your metabolome and proteome describe what is happening right now. Analyzed in isolation, they are separate reports. Analyzed together, patterns emerge across layers that no single test can show.
Learn more about our scienceAre labs included in the fee?
Yes. Advanced omic testing is included in your audit. The fee also covers physician time, interpretation, and program design. Optional add-on testing and imaging are billed separately.
Is the membership required?
No. The Biological Audit and Biological Audit Elite are complete one-time evaluations. The Ongoing Optimization Membership is an optional continuation for those who want quarterly re-measurement and physician-guided adjustment, and it is priced separately.
Why is capacity limited?
Each program requires direct physician time for interpretation, strategy, and ongoing adjustment. Concierge is capped at fifty patients per year so that level of attention remains possible. Audit and Elite open as capacity allows.
The Biological Audit® at the Institute for Human Optimization
Your Biology, Decoded with Precision
If you are ready to move beyond generic checkups and fragmented testing, the Biological Audit; offers a physician-led, data-rich evaluation of how you are truly aging; and what to do about it. One comprehensive program. One clear roadmap for your next decade of health.
Request a ConsultationEvery audit is personally overseen by Anil Bajnath, MD. Capacity is limited.
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