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AGING BRAIN – PART 2: A New Perspective

Cognitive decline does not have to be a consequence of aging. There are ways to intercept and mediate our lifestyle to encourage the growth of new brain cells!

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In Part 1 of our Aging Brain series, we showed how the accumulation of amyloid beta in the brain, the effects of oxidative stress, and the lack of a special nutrient called acetylcholine can all contribute to our brain degenerating over time. Today, we will delve into more ways that affect the health of our brain and functional cognition.

The inflammatory response

Both infectious and non-infectious stimuli activate inflammation in the body, which can be caused by pathogens, toxins, and damaged cells, among dozens of other reasons. The body perceives these as a threat and uses inflammation as a protective mechanism that triggers the immune system to remove the stimuli and initiate the healing process. In an acute situation, this inflammatory process works efficiently to bring the body back into balance. It is when the threatful stimuli become chronic that the inflammatory process becomes overly activated and eventually harmful.

As discussed in Part 1, the brain’s protective inflammatory response is to produce amyloid, which has repeatedly been shown to contribute to cognitive decline. This accumulates over time because of constant threats and assaults on the brain via the way we live our lives. And although evidence indicates that amyloid beta has antimicrobial effects and is made to initially protect our brains, it eventually overreacts and interferes with nerve synapses.

It is because of this accumulation that it is critically important to mediate inflammation by focusing on the foods we eat, moving our bodies, and other supporting ways to keep our brains healthy!

Insight on diet

On page 144 in my book, The Longevity Equation, I talk about how, “Many toxins found in food can cause long-term and irreversible brain damage. And it’s likely you have already encountered some of them. But as the old saying goes: The best time to plant a tree was 20 years ago; the second-best time is now. Although you can’t undo the past, you can start to eliminate neurotoxic substances, optimize your neurotransmitter levels, and ignite the growth of healthy new brain cells for a healthier brain today.”

There is much evidence on the connection between a healthy diet and cognitive function. One pair of researchers found that the Mediterranean diet pattern and the Dietary Approach to Stop Hypertension (DASH) are both “neuroprotective, with potential to delay cognitive decline.”

The European Food Information Council defines the Mediterranean diet pattern as “generally characterized by a high intake of plant-based foods (e.g. fresh fruit and vegetables, nuts, and cereals) and olive oil, a moderate intake of fish and poultry, and low intakes of dairy products (mostly yogurt and cheese), red and processed meats, and sweets.”

The Mayo Clinic states that the DASH diet “encourages you to reduce the sodium in your diet and eat a variety of foods rich in nutrients that help lower blood pressure, such as potassium, calcium, and magnesium…The DASH diet include lots of whole grains, fruits, vegetables and low-fat dairy products. [It] also includes some fish, poultry and legumes, and encourages a small amount of nuts and seeds a few times a week. You can eat red meat, sweets and fats in small amounts. [It] is [also] low in saturated fat, trans fat and total fat.”

Movement is essential

Physical exercise is known to have a protective factor for neurodegeneration. In The Longevity Equation, I state that “Exercise is the key to staying mobile well into old age. It’s also one of the most important things for reducing stress, relieving pain, and keeping your cells healthy.” (p. 116)

And on page 152 in my book, I explore how “a 2008 study literally states that ‘exercise is brain food.’ Though you don’t ingest it, exercise is one of the best things you can do to help keep your brain healthy. Physical activity completely changes the way your brain functions. It helps increase neuroplasticity, which is the brain’s ability to create new synaptic connections…Exercise also helps reduce your risk of stroke and increase the hormones that support brain development, happiness, and overall cognition.”

A new perspective

Professor Dale Bredesen, an internationally recognized expert in the mechanisms of neurodegenerative diseases, challenged existing research in 2014 with a peer-reviewed medical publication entitled Reversal of cognitive decline: a novel therapeutic program. He shared how his unique approach led to the reversal of cognitive decline in nine out of ten patients. Several years later, Dr. Bredesen and his team published Reversal of cognitive decline: 100 patients in which they “describe 100 patients with cognitive decline treated with this multi-component, precision medicine approach, and showing documented improvement.”

The Bredesen Protocol “is based on over three decades of Dr. Bredesen’s laboratory research, resulting in hundreds of peer-reviewed publications that have uncovered the biochemical mechanisms behind the erosion of memory…He’s identified over 36 factors (metabolic derangement, poor nutrient status, lack of trophic support, exposure to viruses, etc.) that can trigger “downsizing” in the brain, all of which can be addressed by using the Bredesen Protocol® designed to prevent cognitive decline …”

Remember our cause for hope

In addition to controlling inflammation, diet, exercise, and the Bredesen Protocol®, I’ve developed a state-of-the-art cognitive supplement perfect for anyone looking to enjoy crystal clear thinking, rapid memory, and a clear memory that won’t let them down.

Puromind provides you with the nutrients you need to maintain healthy, sharp, lifelong cognitive health. You will find an improved ability to recall the things most important to you, enjoy a heightened sense of well-being and peace of mind, and benefit from your mind operating better than it ever has. If you want to learn a new language, have a sharper wit, or simply want to stop dealing with those annoying ‘senior’ moments that interrupt your life, Puromind can give your brain the fuel it needs to function at 100%.

We manufacture each premium batch in an FDA-compliant, GMP-certified facility right here in the USA, and every bottle is tested for both purity and potency, so you can know that you are putting only the most nutritious, beneficial ingredients into your body. Puromind is crafted with the following five powerful, brain-boosting nutrients:

·         LION’S MANE MUSHROOM: In a clinical trial at Tohoku University in Japan, researchers found that the group of people who received lion’s mane mushroom ‘showed significantly increased scores on the cognitive function scale compared with the placebo group,’ and had no side effects!

·       BACOPA MONNIERI: In a study published in the journal, Neuropsychopharmacology, researchers revealed that of the 76 adults aged between 40 and 65 involved in the study, the group that received 300 mg of bacopa daily had improved their memory recall and retention by 100%!

·         ALPHA-GPC:  A study published in the journal, Clinical Therapeutics, found that patients who supplemented with alpha-GPC experienced a dramatic improvement in their memory and ability to perform cognitive tasks.

·         HUPERZINE A: Huperzine A protects acetylcholine from being broken down by your body and can help you maintain healthy acetylcholine levels. A clinical trial performed at the Traditional Chinese Medicine Epicenter in Shanghai found that 58% of patients who took Huperzine A showed 36% memory improvements compared to placebo!

·         GINKGO BILOBA: Ginkgo biloba boosts cerebral blood flow and makes it easier for your brain to absorb Puromind’s other ingredients, magnifying their powerful effects and delivering maximum cognitive support potential. Clinical studies also show that ginkgo is able to dramatically boost blood flow to your brain and the rest of your body almost immediately after taking it.

(These statements have not been evaluated by the FDA. Puromind is not intended to diagnose, treat, cure or prevent any disease.)

How can The Institute for Human Optimization assist me?

At The Institute for Human Optimization, my team and I leverage the most cutting-edge advances in genetic testing, nutritional, and functional medicine to help our patients treat the root biological imbalances that cause aging. I believe that a long healthspan – not just a long lifespan – is the most important thing you can cultivate. A long healthspan means you don’t miss out on life as you get older. It means remaining independent and having the vitality to travel and see the world.  A long healthspan means that you can be there – in full body and mind – for the people who need you the most and that every day will feel like a gift.

The Institute for Human Optimization provides the most comprehensive, data-driven, personalized approach to wellness. It is:

·         Predictive – We use genomics and advanced biomarker testing to risk stratification and empowerment.

·         Personalized – We use data-driven health information to curate actionable change for disease mitigation and prevention.

·         Preventive – We utilize highly individualized programs tailored to your unique genomic blueprint.

·         Participatory – We empower engagement in personal choices, which allows for improved outcomes and enhanced results.

Let’s work together to make a long healthspan your reality!

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