Entries by Anil Bajnath

OMICS OF MEDICINE: Transcriptomics

A gateway to a better understanding of disease pathogenesis. As technology in genomic analysis has enhanced, so has our ability to learn about DNA, RNA, and how they react as we age. With recent developments, we can provide more precise medicine and utilize transcriptomics as a gateway to a better understanding of disease pathogenesis.  .  […]

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THE OMICS OF MEDICINE

The advent of high-throughput technologies in the field of genomic sciences and systems biology has brought about a revolution in primary prevention.  From the early era of sequencing when short genomic reads were being characterized to the current era where the idea of personalized genomes has become a possibility, science has progressed tremendously. Omics refers […]

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ALTERED INTERCELLULAR COMMUNICATION – Where Inflammation Meets Aging

As we age, cells show an increase in self-preserving signals that result in damage elsewhere in the body. Altered intercellular communication contributes to symptoms and diseases that are associated with declining health. .  .  . Today, we conclude our nine-part series on the Hallmarks of Aging. If you have followed along, you will find that […]

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STEM CELL EXHAUSTION – The Ultimate Culprit of Aging

Stem cells have exceptional abilities to self-renew and recreate functional tissues. When this regenerative potential begins to decline in our bodies, many researchers believe it is the defining moment when we begin to see age-related conditions manifest. . . . We have written about seven of the nine Hallmarks of Aging. The first four are […]

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MITOCHONDRIAL DYSFUNCTION: Our Powerhouse Gone Awry

Mitochondria serve as the powerhouses of our cells for which a delicate balance of energy flow is needed to generate energy production. Mitochondrial function has a substantial impact on the aging process and its dysfunction can accelerate aging. . . . The biological definition of aging is the many processes of cellular damage accumulation in […]