Our environment can drive disease or mitigate disease risk. As we look at medicine through the lens of a systems biology approach, most disease is a result of a complex interchange between genetic and environmental factors. . . . The exposome is the sum of all the exposures of an individual in a lifetime and […]
The technology surrounding proteomics has evolved in recent years providing promising new directions to study for future clinical application and in the pursuit of precision medicine. Moreover, advanced proteomic technology has allowed researchers the platform to improve our understanding of biology. . . . What is proteomics? Proteomics refers to the study of proteomes. Proteomes […]
A gateway to a better understanding of disease pathogenesis. As technology in genomic analysis has enhanced, so has our ability to learn about DNA, RNA, and how they react as we age. With recent developments, we can provide more precise medicine and utilize transcriptomics as a gateway to a better understanding of disease pathogenesis. . […]
A blueprint of a genetic “you”. … Our DNA determines an overwhelming amount of information about who we are, but other factors can also influence our health expression. Over the past few decades, the science and technology, and their applications in genomic have made breakthrough progress. Genomic data and genomic medicine services have become relevant […]
The advent of high-throughput technologies in the field of genomic sciences and systems biology has brought about a revolution in primary prevention. From the early era of sequencing when short genomic reads were being characterized to the current era where the idea of personalized genomes has become a possibility, science has progressed tremendously. Omics refers […]
As we age, cells show an increase in self-preserving signals that result in damage elsewhere in the body. Altered intercellular communication contributes to symptoms and diseases that are associated with declining health. . . . Today, we conclude our nine-part series on the Hallmarks of Aging. If you have followed along, you will find that […]
Stem cells have exceptional abilities to self-renew and recreate functional tissues. When this regenerative potential begins to decline in our bodies, many researchers believe it is the defining moment when we begin to see age-related conditions manifest. . . . We have written about seven of the nine Hallmarks of Aging. The first four are […]
Our bodies have a built-in process that is believed to be a protective mechanism called cellular senescence. As we age, this process slows down and can result in disease. . . . The biological definition of aging is the many processes of cellular damage accumulation in the body. These are known in the scientific literature […]
Mitochondria serve as the powerhouses of our cells for which a delicate balance of energy flow is needed to generate energy production. Mitochondrial function has a substantial impact on the aging process and its dysfunction can accelerate aging. . . . The biological definition of aging is the many processes of cellular damage accumulation in […]
