EBOO Therapy in Maryland  /  Extracorporeal Blood Oxygenation & Ozonation

EBOO / EBO2 Therapy Advanced Extracorporeal Blood Filtration & Ozone Therapy

At the Institute for Human Optimization in Maryland, EBOO, or Extracorporeal Blood Oxygenation and Ozonation, is a physician-guided extracorporeal therapy in which blood is circulated outside the body through a specialized system for filtration and controlled exposure to oxygen and ozone before being returned to the circulation. Our approach integrates EBOO within a broader precision and longevity medicine strategy based on individualized evaluation and medical oversight.

Extracorporeal Blood Filtration Blood Oxygenation Controlled Ozonation Physician-Guided Therapy Precision Medicine Longevity Medicine
The Three Components

What Is EBOO / EBO2 Therapy?

EBOO, or Extracorporeal Blood Oxygenation and Ozonation, is a physician-guided extracorporeal therapy in which blood is circulated outside the body through a specialized closed-loop system. During the procedure, blood passes through filtration and is exposed to a carefully controlled mixture of medical oxygen and ozone before being returned to the circulation. At the Institute for Human Optimization, EBOO may be incorporated into an individualized regenerative and longevity medicine strategy following appropriate medical evaluation.

Extracorporeal blood filtration during EBOO therapy in Maryland

Extracorporeal Filtration

During EBOO therapy, blood continuously circulates through an extracorporeal filtration system before returning to the body. This filtration component distinguishes EBOO from conventional ozone autohemotherapy and allows a larger volume of circulating blood to be processed during a treatment session.

Extracorporeal blood oxygenation and ozonation during EBOO therapy

Oxygenation & Ozonation

Within the extracorporeal circuit, circulating blood is exposed outside the body to a controlled oxygen-ozone gas mixture. Ozone rapidly interacts with components of the blood rather than being administered directly into the bloodstream. These biochemical interactions and their potential effects on oxidative and cellular signaling pathways continue to be investigated.

Hemealumen extracorporeal photobiomodulation used with EBO2 therapyWhen clinically selected

Extracorporeal Photobiomodulation

When incorporated into the treatment protocol, the Hemealumen system can expose circulating blood outside the body to multiple controlled wavelengths of light, including visible and ultraviolet wavelengths. This adjunctive photobiomodulation step is designed to complement the filtration and oxygen-ozone components of the extracorporeal procedure.

EBOO is more than conventional ozone autohemotherapy.It combines extracorporeal circulation, filtration, controlled oxygen-ozone exposure, and, when clinically selected, extracorporeal photobiomodulation within one physician-guided treatment platform.

How EBOO / EBO2 Therapy Works

The Extracorporeal Circuit

EBOO, or Extracorporeal Blood Oxygenation and Ozonation, uses a closed extracorporeal circuit to continuously circulate blood outside the body through a specialized treatment system. Blood moves through filtration and controlled oxygen-ozone exposure before being returned to the circulation. When clinically selected, extracorporeal photobiomodulation may also be incorporated into the procedure.

  1. Step 01

    Extracorporeal Circulation

    Vascular access allows blood to enter a sterile, closed extracorporeal circuit. Blood flow is carefully controlled throughout the procedure as it moves through the EBOO system before returning to the circulation.

  2. Step 02

    Extracorporeal Filtration

    As blood moves through the extracorporeal circuit, it passes through a specialized filtration component. This continuous filtration step is one of the features that distinguishes EBOO from conventional ozone autohemotherapy.

  3. Step 03

    Oxygen-Ozone Gas Exchange

    Within the extracorporeal system, circulating blood is exposed outside the body to a precisely controlled medical oxygen-ozone gas mixture. This allows the oxygen-ozone interaction to occur within the treatment circuit rather than through direct intravenous administration of ozone gas.

  4. Step 04

    Controlled Ozonation

    Ozone rapidly reacts with components of the blood within the extracorporeal circuit, generating downstream biochemical signals that are being investigated for their potential effects on oxidative, inflammatory, and cellular signaling pathways.

  5. Step 05When clinically selected

    Extracorporeal Photobiomodulation

    When incorporated into the treatment protocol, the Hemealumen system can expose circulating blood outside the body to multiple controlled wavelengths of visible and ultraviolet light. This adjunctive step complements the extracorporeal filtration and oxygen-ozone components of the procedure.

  6. Step 06

    Return to Circulation

    After completing the extracorporeal treatment circuit, the processed blood is continuously returned to the patient. The procedure is performed under clinical supervision with treatment parameters selected according to the patient’s medical evaluation and individualized protocol.

Patient Experience

What to Expect During EBOO / EBO2 Therapy

At the Institute for Human Optimization, EBOO (Extracorporeal Blood Oxygenation and Ozonation) is a physician-guided procedure performed in a monitored clinical setting. Treatment is individualized based on your medical evaluation, health history, and goals. While protocols vary, most EBOO appointments follow a similar process from preparation through post-treatment care.

Before

Preparing for EBOO Therapy

Patients are generally encouraged to arrive well hydrated and follow any preparation instructions provided by the clinical team. Medication, supplement, food, and hydration instructions may vary based on your medical history and individualized treatment plan.

During

EBOO Treatment Duration

Most EBOO appointments last approximately 60 to 90 minutes, although treatment time can vary depending on the individualized protocol and whether additional modalities, such as extracorporeal photobiomodulation, are included.

After

After Your EBOO Session

After treatment, your clinical team will provide individualized post-procedure instructions and review any recommended next steps. Hydration, activity, and follow-up recommendations are based on your treatment response and overall clinical plan.

Ongoing

Treatment Frequency

There is no one-size-fits-all EBOO schedule. Treatment frequency is determined individually and may be adjusted based on clinical response, relevant laboratory data, treatment tolerance, and the goals established with your care team.

Patient Experience

What to Expect During EBOO / EBO2 Therapy

At the Institute for Human Optimization, EBOO (Extracorporeal Blood Oxygenation and Ozonation) is a physician-guided procedure performed in a monitored clinical setting. Treatment is individualized based on your medical evaluation, health history, and goals. While protocols vary, most EBOO appointments follow a similar process from preparation through post-treatment care.

Before

Preparing for EBOO Therapy

Patients are generally encouraged to arrive well hydrated and follow any preparation instructions provided by the clinical team. Medication, supplement, food, and hydration instructions may vary based on your medical history and individualized treatment plan.

During

EBOO Treatment Duration

Most EBOO appointments last approximately 60 to 90 minutes, although treatment time can vary depending on the individualized protocol and whether additional modalities, such as extracorporeal photobiomodulation, are included.

After

After Your EBOO Session

After treatment, your clinical team will provide individualized post-procedure instructions and review any recommended next steps. Hydration, activity, and follow-up recommendations are based on your treatment response and overall clinical plan.

Ongoing

Treatment Frequency

There is no one-size-fits-all EBOO schedule. Treatment frequency is determined individually and may be adjusted based on clinical response, relevant laboratory data, treatment tolerance, and the goals established with your care team.

Investment

EBOO / EBO2 Therapy Pricing

EBOO is a physician-guided extracorporeal therapy. Treatment recommendations are individualized based on your medical evaluation, clinical goals, and overall regenerative medicine plan.

Start here

Regenerative Medicine Consultation

$60060 minutes

A comprehensive 60-minute consultation to review your medical history, goals, and potential suitability for EBOO / EBO2 and other regenerative medicine strategies.

Established patients of the Institute for Human Optimization may not require a separate consultation. Please contact the clinical team through the Patient Portal.

Request a Consultation
Single treatment

Single EBOO / EBO2 Session

$1,800per session

A physician-guided EBOO session incorporating extracorporeal circulation, filtration, and controlled oxygen-ozone exposure. Additional modalities, including extracorporeal photobiomodulation, may be incorporated when selected as part of your individualized protocol.

Ask About a Session
Save $900 Series

3-Session EBOO / EBO2 Series

$4,500$1,500 per session

For patients whose individualized treatment plan includes multiple EBOO sessions. Treatment timing and frequency are determined by the clinical team based on your evaluation, response, and overall care plan.

Ask About the Series
  • Treatment follows a medical evaluation; not every patient is a candidate.
  • Cash pay practice. We do not bill insurance for this service.
  • Prices are subject to change. Deposit policy
Investment

EBOO / EBO2 Therapy Pricing

EBOO is a physician-guided extracorporeal therapy. Treatment recommendations are individualized based on your medical evaluation, clinical goals, and overall regenerative medicine plan.

Start here

Regenerative Medicine Consultation

$60060 minutes

A comprehensive 60-minute consultation to review your medical history, goals, and potential suitability for EBOO / EBO2 and other regenerative medicine strategies.

Established patients of the Institute for Human Optimization may not require a separate consultation. Please contact the clinical team through the Patient Portal.

Request a Consultation
Single treatment

Single EBOO / EBO2 Session

$1,800per session

A physician-guided EBOO session incorporating extracorporeal circulation, filtration, and controlled oxygen-ozone exposure. Additional modalities, including extracorporeal photobiomodulation, may be incorporated when selected as part of your individualized protocol.

Ask About a Session
Save $900 Series

3-Session EBOO / EBO2 Series

$4,500$1,500 per session

For patients whose individualized treatment plan includes multiple EBOO sessions. Treatment timing and frequency are determined by the clinical team based on your evaluation, response, and overall care plan.

Ask About the Series
  • Treatment follows a medical evaluation; not every patient is a candidate.
  • Cash pay practice. We do not bill insurance for this service.
  • Prices are subject to change. Deposit policy
Safety  /  Patient Selection  /  Clinical Oversight

A Physician-Guided Approach to EBOO / EBO2

EBOO at the Institute for Human Optimization is approached as a medical procedure requiring thoughtful patient selection, individualized treatment planning, and clinical monitoring. Your health history, medications, relevant laboratory data, and treatment tolerance are considered before and during therapy.

  1. 01Before

    Individualized Patient Screening

    Medical history, medications, relevant laboratory findings, and potential contraindications are reviewed before treatment to determine whether EBOO is appropriate for you.

  2. 02Before

    Physician-Guided Treatment Planning

    Treatment recommendations, session frequency, and any additional modalities are selected according to your clinical evaluation and individualized care plan.

  3. 03During

    Clinical Monitoring

    Your vital signs, comfort, vascular access, and overall treatment tolerance are monitored throughout the extracorporeal procedure.

  4. 04Every session

    Sterile, Single-Use Treatment Circuit

    EBOO is performed using a sterile extracorporeal circuit with single-use treatment components in accordance with the protocol used for your procedure.

Regenerative Medicine at the Institute for Human Optimization

Is EBOO Right for Your Biology?

EBOO is not approached as a one-size-fits-all therapy at the Institute for Human Optimization. Your journey begins with a physician-guided evaluation to understand your health history, biological data, goals, and whether EBOO belongs within your broader regenerative and longevity medicine strategy.

Established patients of the Institute for Human Optimization interested in EBOO may contact the clinical team through the Patient Portal.

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